Stromal Vascular Fraction (SVF) from Fat

Complex cell suspension that is manually isolated by bioengineering techniques from the fat tissue in the abdomen, usually in the laboratory environment under GMP conditions; Fat-derived stromal cells are also called stromal vascular fraction (SVF). adipose tissue; It contains concentrated amounts of multipotent progenitors, mesenchymal stem cells (regenerative cells), endothelial progenitor cells, and vascular smooth muscle cells when isolated by validated enzymatic and mechanical techniques under GMP conditions.

SVF contains many different stem cell sources and active biomolecules (growth factors), being ready in a shorter time compared to cultivation methods; This has made it more advantageous compared to stem cell sources such as bone marrow and cord blood, and paved the way for it to be used in many different health problems. It should be noted that SVF is not a cultured pure stem cell application, it consists of a mixture of cells. Because; frequently pronounced in advertisements and promotions in the market; The statements “SVF is a stem cell application” do not reflect the truth scientifically.

Fat graft; Although it has been discovered since the 19th century and is widely used in aesthetic operations today, stromal cell extraction from adipose tissue (SVF) has gained value in recent years and has become a more advantageous cellular application method compared to bone marrow and cord blood.

SVF; In addition to many various cell types, it also contains many growth factors (EGF, VEGF, bFGF), thus increasing angiogenesis (vessel formation), providing oxygen and nutrient transport to the injected area and activating repair mechanisms.

SVF; When administered to the systemic circulation, it can provide regulation of endothelial intercellular signals, restructuring of protein structures that provide vessel flexibility and permeability. In this respect, there are scientific publications on its use in the treatment of patients with circulatory disorders.

ADVANTAGES

Since it is obtained from the person's own fat tissue, allergic side effects are not expected.
It contains at least 3 times more and a rich variety of stem cells* compared to bone marrow and cord blood; therefore, the efficacy of the treatment is expected to increase. (* Comparison was made based on the same volume of tissue and provided that cells were obtained by enzymatic and mechanical isolation techniques under GMP conditions)
Adipose tissue uptake is easier than bone marrow.
For patients who cannot wait for the cultivation period, max. The application is carried out within 48 hours.
While the patient gets rid of the unwanted fat in the abdomen or hip area, on the other hand, he gets the treatment he needs.
Since it contains a rich variety of cell populations, it can be used in many different diseases.
It is non-toxic, does not contain synthetic components.

Usage areas

Treatment of chronic wounds (diabetes, pressure, venous ulcer, polyarteritis nodosa, etc.) that do not close,
Treatment of erectile dysfunction (impotence),
Treatment of neurodegenerative diseases (MS, Alzheimer's, ALS, Parkinson's, SMA, Autism),
Anti-aging applications,
Strengthening the pelvic muscles in breast enlargement, penis and vagina aesthetics,
Applications in the fields of baldness treatment and aesthetic therapy.
For the treatment of autoimmune diseases,
Type-1 and Type-2 diabetes treatment,
Joint, cartilage wear, meniscus, tendon and connective tissue injuries,
In osteoarthritis, chronic wrist sprains,
Treatment of nonunion fractures, waist treatment, degenerative cartilage diseases, intervertebral disc degeneration,
Filling the pits formed after ailments such as acne or chickenpox,
Treatment of cavities and scars due to burns, previous surgery or trauma,
To plump the lips
It can be used to support the treatment of muscle tears.

*The multi-functionality of the stem cell from fat (SVF) has brought the advantage of being used in many different indications. However, it should be known that the person's condition, age, course of the disease, genetic predispositions and many other factors will affect the success of this treatment, and the application decision should be made as a result of the doctor's evaluation. SVF is not a cell application with proven efficacy in all the above-mentioned indications. For this reason, cellular applications used for therapeutic purposes on Earth are still considered experimental. However, there are scientific and clinical publications showing that these products can be used in many treatments and positive results can be obtained.